| 中文名 | 非那甾胺 |
| 英文名 | finasteride |
| 别名 | 非那甾铵 非那甾安 非那甾胺 非那雄胺 非那雄胺(标准品) 非那甾胺(FTD) 非那雄胺, 一种睾酮5Α-还原酶抑制剂 N-叔丁基-3-氧代-4-氮杂-5Α-雄甾-1-烯-17Β-甲酰胺 N-叔丁基-3-氧代-4-氮杂-5a-雄甾-1-烯-17b-甲酰胺 |
| 英文别名 | mk-0906 proscar l-652,931 finasteride 17beta-(n-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one n-tert-butyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide n-(2-methyl-2-propyl)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide (5alpha,17beta)-(1,1-dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide 4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5alpha,17beta (5alpha,17beta)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide 4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5-alpha,17-be (4aR,4bS,6aS,7S,9aS,9bS)-N-tert-butyl-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]xamide (4aR,4bS,6aS,9aS,9bS,11aR)-N-tert-butyl-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]xamide |
| CAS | 98319-26-7 |
| EINECS | 620-534-3 |
| 化学式 | C23H36N2O2 |
| 分子量 | 372.54 |
| InChI | InChI=1/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18?,22-,23+/m0/s1 |
| InChIKey | DBEPLOCGEIEOCV-WSB |
| 密度 | 1.065±0.06 g/cm3(Predicted) |
| 熔点 | 253 °C |
| 沸点 | 576.6±50.0 °C(Predicted) |
| 比旋光度 | 405 -59° (c = 1 in methanol) |
| 闪点 | 177.448°C |
| 水溶性 | insoluble |
| 蒸汽压 | 0mmHg at 25°C |
| 溶解度 | DMSO: 32mg/mL, soluble |
| 折射率 | 1.524 |
| 酸度系数 | 14.17±0.70(Predicted) |
| 存储条件 | room temp |
| 外观 | solid |
| 颜色 | white to beige |
| Merck | 14,4082 |
| 物化性质 | 白色或类白色结晶性固体。易溶于氯仿、二甲亚砜、乙醇、甲醇或正丙醇，难溶于丙二醇或聚乙二醇400，极微溶于0.1mol/L盐酸、0.1mol/L氢氧化钠溶液或水。熔点约257℃；也有熔点252～254℃。[α]D-59°(C=l，甲醇)。 |
