中文名 | 己酸孕酮 |
英文名 | 17A-hydroxyprogesterone hexanoate |
别名 | 己酸孕酮 已酸朵酮 已酸孕酮 己酸羟孕酮 长效黄体酮 己酸孕酮× 17-羟已酸孕酮 己酸孕酮(标准品) 17 -Α-羟基黄体酮CAPROATE |
英文别名 | HydroxyprogesteroneCaproate Hydroxyprogesterone caproate HYDROXYPROGESTERONECAPROATE,USP 17A-Hydroxyprogesterone Caproate PREGN-4-ENE-3,20-DIONE HEXANOATE 17α-Hydroxyprogesterone hexanoate 17A-hydroxyprogesterone hexanoate 17α-Hydroxyprogesterone n-caproate 17α-Caproyloxypregn-4-ene-3,20-dione 3,20-dioxopregn-4-en-17-yl hexanoate 3,20-Dioxopregn-4-en-17α-yl caproate 17alpha-Hydroxyprogesterone caproate 3,20-dioxopregn-4-en-17-alpha-yl hexanoate (8xi,9xi,14xi)-3,20-dioxopregn-4-en-17-yl hexanoate (8xi,10xi,13xi)-3,20-dioxopregn-4-en-17-yl hexanoate Pregn-4-ene-3,20-dione, 17-hydroxy-, hexanoate (7CI, 8CI) Hexanoic acid, ester with 17-hydroxypregn-4-ene-3,20-dione(8CI) |
CAS | 630-56-8 |
EINECS | 211-138-8 |
化学式 | C27H40O4 |
分子量 | 428.6 |
InChI | InChI=1/C27H40O4/c1-5-6-7-8-24(30)31-27(18(2)28)16-13-23-21-10-9-19-17-20(29)11-14-25(19,3)22(21)12-15-26(23,27)4/h17,21-23H,5-16H2,1-4H3/t21?,22?,23?,25-,26-,27-/m0/s1 |
InChIKey | DOMWKUIIPQCAJU-LJHIYBGHSA-N |
密度 | 1.0148 (rough estimate) |
熔点 | 119°C |
沸点 | 463.43°C (rough estimate) |
比旋光度 | +44~+50°(D/20℃)(c=1,CH3OH) |
闪点 | 227.6°C |
蒸汽压 | 1.4E-11mmHg at 25°C |
溶解度 | Chloroform (Slightly), Methanol (Slightly) |
折射率 | 1.4840 (estimate) |
存储条件 | Sealed in dry,Room Temperature |
外观 | Solid |
颜色 | Off-White |
Merck | 4839 |
MDL号 | MFCD00072134 |
体内研究 | 对受孕大鼠处理以Hydroxyprogesteronecaproate来检测其超常水平的腹腔注射对第一代雄性生殖潜能的作用。在大鼠胚胎发育时期处理以Hydroxyprogesteronecaproate,其尾附睾精子数目及其运动性均显著降低。在胚胎期处理后,成年大鼠将出现血清睾酮水平下降,促卵泡激素和黄体化激素升高的现象。 |